Marc Rodriguez spent his formative years in east Tennessee and his teenage years in south Florida, an area heavily influenced by Cuban immigrants. Marc's father was one of the immigrants who moved with his family to south Florida to escape Castro's regime. Marc graduated from Florida Atlantic University in 2004 with bachelors degree in fine arts majoring in sculpture. During this period he exhibited his work in numerous student shows, a show in Delray Beach, and a show in Fort Lauderdale.

Marc's most significant work during his time at the University began with a series of sculptures using industrial steel rusted rods that penetrated spherical concrete structures. He called these pieces "drop bombs." Many of these pieces were assembled onto pyramidal steel bases giving the impression of primitive drawings of people, the head being the "drop bomb." His next series began with a similar primitive feel using rusted steel rods and rusted wire. He used the wire and rods as a way to cage in objects to give an affect of inacessibility. You can see it through the wire but
you will never be able to access the object in its more "pure" form. This notion of "pure" became a focal point of Marc's artwork. The purest object for Marc became the extraneous matter of the object. The object itself cannot be pure. It is the excess that points to the pure.

For his next series Marc further explored this notion of purity by focusing on the excess or debris of the object. He focused on human consumption and excessive waste. He collected roadside litter from each state on the east coast, beginning in Miami and ending in Maine, after which he encased the litter in large clear tubes. His main objective in collecting litter was to use the more pure excess in a way that would give the viewer a sense of this purity by putting the collected litter in large clear tubes. These large tubes of detritus gave the viewer a sense that a monument was dedicated to humanity's waste.

In May of 2007 in the Drive-Thu Art Show in Knoxville Marc exhibited a piece from his series of rusted wires and rods, possibly his most significant piece during that time where he enclosed a metal and wood school desk with rusted rebar wire. After enclosing the desk, he welded together steel rods into a box structure and then wrapped over four miles of wire around it. This structure became a cage for the wired school desk.

Next, Marc has taken some of his ideas from his earlier pieces and applied them on a more personal, national, and global scale. Using the more two dimensional surface of the canvas, he has taken fragments of his past and juxtaposed them with the present atrocities occurring throughout the world. These fragments take the form of pills, pill bottles, photographs, and remote controls,
which have been either decoupaged directly onto the canvas or drawn with ink.  His more recent ink drawings consist of contorted architectural structures, laden with uniform television panels,surveillance cameras, and ballastic missiles.  The architectural structures are processing centers that feed, contain, and regurgitate trash.